Guides

Peptide Guides

Educational guides explaining what different peptides are and how they work.

Showing 36 guides

Other

Are Peptides Safe?

An honest overview of peptide safety, distinguishing between approved medications and research compounds.

Other

Clinical Trial Phases: A Guide to the Terms

A plain-language reference for preclinical research, Phases 1 through 4, and the separate FDA review step.

Metabolic

GLP-1 Receptor Agonists: A Guide to the Drug Class

A plain-language guide to GLP-1 receptor agonists, how their actions differ from tirzepatide, and why each U.S. brand has its own approved uses.

Metabolic

How GLP-1 Agonists Work in the Body

A plain-language explanation of GLP-1 receptor signaling in the pancreas, gut, and appetite system, with the safety and product differences that matter.

Other

How Peptides Work: A Receptor and Signaling Primer

A beginner's guide to peptide receptor binding, cell signaling, and why one peptide's behavior cannot stand for every peptide.

Other

How to Read an Animal Study About Peptides

A practical checklist for judging what an animal study reports and which human questions it leaves unanswered.

Other

How to Read Peptide Research

A practical guide to evaluating peptide research claims and understanding what studies actually show.

Other

Peptide Evidence Levels Explained

A reference for reading the four evidence-strength labels on PepCodex and the limits of each label.

Other

Peptides and Proteins: A Terminology Guide

A short guide to amino acids, peptide bonds, polypeptides, and proteins, including why a fixed size cutoff is only a convention.

Hormonal

What Are GH Secretagogues?

An introduction to growth hormone secretagogues, compounds that stimulate the body to release growth hormone.

Longevity

What Are Longevity Peptides?

An introduction to peptides marketed for anti-aging and longevity, including Epitalon and thymic peptides.

What Are Nootropic Peptides?

An introduction to peptides marketed for cognitive enhancement, including Semax, Selank, and Dihexa.

Repair & Recovery

What Are Recovery Peptides?

An introduction to peptides marketed for tissue repair and recovery, including BPC-157 and TB-500.

Repair & Recovery

What is BPC-157?

An introduction to BPC-157, its origins, claims, and important limitations.

About bpc-157
Hormonal

What is CJC-1295?

An introduction to CJC-1295, a modified GHRH analog designed for longer-lasting effects.

About cjc-1295

What is Dihexa?

An introduction to dihexa, an experimental nootropic peptide studied for cognitive effects.

About dihexa
Longevity

What is Epithalon?

An introduction to epithalon, a synthetic tetrapeptide studied for potential effects on telomeres.

About epithalon
Repair & Recovery

What is GHK-Cu?

An introduction to GHK-Cu (copper peptide), the naturally occurring peptide used in skincare.

About ghk-cu
Longevity

What is Humanin?

An introduction to humanin, a naturally occurring mitochondrial-derived peptide with protective properties.

About humanin
Hormonal

What is Ipamorelin?

An introduction to ipamorelin, a selective growth hormone secretagogue that was never approved.

About ipamorelin

What is LL-37?

An introduction to LL-37, a human antimicrobial peptide with emerging research on immune function.

About ll-37
Other

What is Melanotan II?

An introduction to Melanotan II, the unapproved tanning peptide with serious safety warnings.

About melanotan-ii
Hormonal

What is MK-677?

MK-677 (ibutamoren/LUM-201) is an investigational oral growth-hormone secretagogue with established hormonal effects but uncertain clinical benefit.

About mk-677
Metabolic

What is Mounjaro?

An introduction to Mounjaro, the brand name for tirzepatide approved for type 2 diabetes.

About tirzepatide
Metabolic

What is Ozempic?

An introduction to Ozempic, the brand name for semaglutide approved for type 2 diabetes.

About semaglutide
Hormonal

What is PT-141?

An introduction to PT-141 (bremelanotide/Vyleesi), the FDA-approved treatment for HSDD.

About pt-141
Metabolic

What is Retatrutide?

An introduction to retatrutide, the investigational triple agonist showing promising weight loss results.

About retatrutide
Metabolic

What is Rybelsus?

An introduction to Rybelsus, the oral tablet form of semaglutide for type 2 diabetes.

About semaglutide
Metabolic

What is Semaglutide?

An introduction to semaglutide, the GLP-1 agonist behind Ozempic and Wegovy.

About semaglutide
Hormonal

What is Sermorelin?

An introduction to sermorelin, a GHRH analog that was once FDA-approved for pediatric growth hormone deficiency.

About sermorelin
Repair & Recovery

What is TB-500?

An introduction to TB-500, a fragment of thymosin beta-4 marketed for tissue repair.

About tb-500
Hormonal

What Is Tesamorelin?

A guide to tesamorelin: the GHRH analog approved for excess abdominal fat in adults with HIV-associated lipodystrophy, its trial evidence and limitations.

About tesamorelin

What is Thymalin?

An introduction to thymalin, a thymic peptide extract studied for immune function.

About thymalin
Metabolic

What is Tirzepatide?

An introduction to tirzepatide, a dual GIP/GLP-1 receptor agonist used for type 2 diabetes and weight management. Learn how it works, what the research shows, and key facts you should know.

About tirzepatide
Metabolic

What is Wegovy?

An introduction to Wegovy, the brand name for semaglutide approved for weight management.

About semaglutide
Metabolic

What is Zepbound?

An introduction to Zepbound, the brand name for tirzepatide approved for weight management.

About tirzepatide