What is TB-500?
An introduction to TB-500, a fragment of thymosin beta-4 marketed for tissue repair.
Last updated: January 28, 2026
What is TB-500?
TB-500 is a synthetic fragment of thymosin beta-4 (Tβ4), a naturally occurring protein involved in cell migration and wound healing. It is not approved by any regulatory agency.
Key Facts
| Fact | Detail |
|---|---|
| Approved | No |
| Parent Compound | Thymosin beta-4 |
| Evidence Level | Low |
| WADA Status | Prohibited |
TB-500 vs Thymosin Beta-4
| Aspect | TB-500 | Thymosin Beta-4 |
|---|---|---|
| Structure | Fragment | Full protein |
| Human Trials | None (TB-500) | Some Phase 2 |
| Research | Limited | More extensive |
What’s Claimed?
TB-500 is marketed for:
- Muscle and tendon healing
- Wound recovery
- Flexibility improvement
The Evidence Problem
- TB-500 specifically has no human clinical trials
- Research on the parent compound (Tβ4) cannot be directly applied
- The fragment may behave differently than the full protein
Important Warnings
- Products are unregulated with unknown purity
- Safety is not established
- Banned in competitive sports
- Gained attention from horse racing scandals
This guide is for educational purposes only. TB-500 is not approved for any medical use.
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Disclaimer: This educational guide does not constitute medical advice. The information presented is based on current research but should not be used for diagnosis, treatment, or prevention of any disease. Always consult a qualified healthcare provider before making health decisions.