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A specimen of the Cognitive drawer Drawer E · Cognitive

Cerluten

Research Only

A cytamin-class peptide supplement derived from brain tissue, part of the Russian bioregulator framework. Marketed as an oral supplement for cognitive support and neuroprotection. Contains peptide complexes rather than defined sequences. No Western clinical validation.

Brain cytamin · Cerebral peptides · A-5 brain peptides

Research evidence
Low

Mostly preclinical · 1 human study

Preclinical
75%
Clinical
13%

Based on 8 cited sources

Evidence Score19/100
Insufficient
Research Depth12/100
Mechanism22/100
Plausibility30/100
Global Coverage18/100
Community Experience14/100
EffectivenessNot Established

Demonstrated effect magnitude — not a recommendation or safety claim.

Research depth low: cytamin-class brain complex with only uncontrolled Russian observational human data and a small preclinical base, no RCTs. Mechanism partial: Khavinson short-peptide gene-regulation framework is characterized for defined peptides but Cerluten is an undefined tissue mixture, weakening target attribution. Plausibility moderate: neuroprotective claims cohere with peptide-bioregulator biology yet rest on unproven oral bioavailability and surrogate links. Global coverage limited: research concentrated in one Russian group with little independent replication. Community experience minimal: negligible documented real-world use. Effectiveness not established: no quantified human efficacy estimate and no meaningful community effect signal.

Scored May 2026 How we rate →
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Evidence Level
low
Not approved for human use by any regulatory agency
Limited human clinical trial data
Consult a healthcare provider before use
Not FDA Approved WADA Prohibited
Identity
Also Known As
Brain cytamin • Cerebral peptides • A-5 brain peptides

Mechanism of Action

Cerluten is a cytamin-class supplement containing peptide complexes derived from brain tissue.

Cytamin Classification

Cytamins are oral supplements in the Russian bioregulator framework:

  • Tissue-derived peptide mixtures
  • Multiple peptide fractions
  • Marketed as dietary supplements
  • Not defined single compounds

Proposed Mechanisms

  1. Neuroprotection - Claimed to support neuronal cell function
  2. Cognitive Support - Proposed effects on memory and cognition
  3. Age-Related Decline - Marketed to address cognitive aging

Important Limitations

  • NOT a defined peptide - contains complex mixture
  • Oral peptide bioavailability is generally very low
  • No Western clinical validation
  • No randomized controlled trials for cognitive outcomes
  • Not approved by any Western regulatory agency
  • NOT a treatment for dementia or cognitive disorders
Mechanism Brain peptide complex supporting neuronal function
Emerging 3 direct studies
Benefit may support cognitive function
Evidence Level
Very Low
1 Human
2 Animal
1 In Vitro
Mechanism Confidence
Established
Supported
Emerging
Evidence Level
High
Moderate
Low
Very Low
Synergistic
Compatible
Caution
Avoid

Both target brain function - Cortexin is injectable brain extract with more clinical data, Cerluten is oral cytamin supplement.

Both target brain/cognitive function - Pinealon is synthetic tripeptide, Cerluten is tissue-derived complex.

Semax

Compatible
Compatible

Both Russian nootropic peptides - Semax is defined heptapeptide with more research, Cerluten is cytamin supplement.

Research Note: Interaction data is based on published literature, mechanistic understanding, and theoretical considerations. Most peptide combinations lack direct clinical study. This information is for educational purposes only and does not constitute medical advice. Always consult qualified healthcare providers.

8 Sources 1 Human 6 Preclinical

Key Studies Cited

Full reference list available on request. All citations link to PubMed for verification.

This dossier synthesizes available evidence from peer-reviewed literature, regulatory documents, and clinical trial registries. Evidence strength ratings follow a modified GRADE approach.

For complete methodology details, see our Methodology page.

Important Disclaimer

This dossier is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.

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