Low Evidence
Research Overview
MOTS-c Research for Aging & Longevity
An evidence-based overview of research examining MOTS-c in the context of aging & longevity. This page synthesizes findings from peer-reviewed literature.
Research Summary
MOTS-c levels decline with age in both mice and humans. Late-life treatment improved physical function in aged mice. The K14Q variant is associated with longevity in Japanese populations. No human therapeutic trials have been conducted.
Referenced Studies
Click any PMID to view the full study on PubMed.
Other Peptides Studied for Aging & Longevity
Important Disclaimer
This page summarizes research findings and does not constitute medical advice. MOTS-c has not received regulatory approval for some indications but should only be used under qualified medical supervision. Always consult a healthcare provider before making health decisions.