Moderate Evidence Research Overview

LL-37 Research for Inflammation

An evidence-based overview of research examining LL-37 in the context of inflammation. This page synthesizes findings from peer-reviewed literature.

Research Summary

LL-37 has complex immunomodulatory effects, functioning as both pro- and anti-inflammatory depending on context. The peptide can neutralize LPS (endotoxin), recruit immune cells, and modulate cytokine production. In excess, LL-37 contributes to inflammatory diseases like rosacea and psoriasis. However, at physiological levels it helps balance immune responses. Understanding LL-37's role in inflammation has led to research into both agonists (for immunodeficiency) and inhibitors (for inflammatory diseases).

Referenced Studies

Click any PMID to view the full study on PubMed.

Other Peptides Studied for Inflammation

Important Disclaimer

This page summarizes research findings and does not constitute medical advice. LL-37 may have regulatory approval for some indications but should only be used under qualified medical supervision. Always consult a healthcare provider before making health decisions.