Epithalon vs Humanin
Comparison of Epithalon (Low evidence) and Humanin (Moderate evidence).
Last updated: February 12, 2026
Epithalon
Humanin
Overview
Epithalon and Humanin are both studied in the peptide research space.
Epithalon: A synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Russian scientist Vladimir Khavinson, claimed to activate telomerase and extend lifespan.
Humanin: A 24-amino acid mitochondria-derived peptide (MDP) discovered in 2001 that shows cytoprotective, anti-apoptotic, and neuroprotective effects in preclinical studies.
Evidence Comparison
| Aspect | Epithalon | Humanin |
|---|---|---|
| Evidence Level | Low | Moderate |
| Human Studies | 5 | 10 |
| Preclinical Studies | 15 | 40 |
| Total Sources | 28 | 50 |
Key Differences
| Aspect | Epithalon | Humanin |
|---|---|---|
| Category | Longevity | Longevity |
| Evidence Strength | Low | Moderate |
| Total Sources | 28 | 50 |
| Human Studies | 5 | 10 |
Summary
- Epithalon: Low evidence with 28 total sources (5 human)
- Humanin: Moderate evidence with 50 total sources (10 human)
This comparison is for educational purposes only and is not medical advice. Consult a healthcare professional before making any decisions about peptide use.
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Disclaimer: This comparison is for educational purposes only and does not constitute medical advice. Individual responses to medications vary. Always consult a qualified healthcare provider before making treatment decisions.